While regulators have concluded modafinil is not addictive and classified it as a non-addictive drug, some scientists feel there is an addiction potential. At the least, it can be psychologically addictive as users enjoy its effects and do not want to go a day without those effects. Physical addiction. The drug affects dopamine levels as do many addictive drugs, but there is no clear physiological model for drug addiction and it is not thought that any increase in dopamine levels necessarily leads to addiction.


No, modafinil does not make people feel “wired” the way other stimulants do. One danger is that it’s ability to forestall fatigue may mask to the user how tired he or she is and how much physical and mental performance falls after an extended period of wakefulness, even under the influence of the medicine.

Modafinil is not a substitute for sleep. It also tends to have better effects if you take it early in the day before you become fatigued, rather than using it to mitigate the effects of fatigue.


Modafinil does not produce mania the way amphetamines can.


Well, maybe not contraindications in the way the medical field usually uses that word, which is to rule out patient eligibility for a treatment. But doctors have to take special consideration when giving the drug to these patients.